Bacterial Pathogenesis


Bacterial pathogenesis is the process by which bacteria infect and cause disease in a host. Not all bacteria are pathogens and have the ability for pathogenesis (also known as virulence). Pathogenic bacteria utilise a number of mechanisms to cause disease in human hosts. Bacterial pathogens express a wide range of molecules that bind host cell targets to facilitate a variety of different host responses. In bacterial host mediated pathogenesis, (e.g., tuberculosis), tissue damage results from the toxic mediators released by lymphoid cells rather than from bacterial toxins.


  • Intracellular growth
  • Bacterial infectivity
  • Bacterial resistance
  • Pathogenic mechanisms

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